| 1715 |
French military reestablish presence at straits and construct Fort Michilimackinac near Odawa community and Jesuit mission on the south side of the straits. |
| 1716 |
Residents of Fort Michilimackinac participate in victorious attack on Fox tribe in Wisconsin. |
| 1728 |
Commandant of Michilimackinac leads combined French, Odawa and Ojibwa force from Michilimackinac into Wisconsin to defeat the Fox. The Fox avoid battle. |
| 1733 |
Another force of French and American Indian allies assembles at Michilimackinac and launches an expedition into Green Bay against the Fox. Commandant of Michilimackinac killed in battle. Expansion of fort begins with new layout for buildings. |
| 1739 |
Michilimackinac serves as base for French expedition against the Chickasaw south of the Ohio River. Despite some success, Chickasaw never decisively defeated. |
| 1742 |
Odawa relocate 25 miles south at L'Arbre Croche. Jesuits transfer St. Ignace mission to new location, but maintain a parish church at Fort Michilimackinac. |
| 1743 |
New parish church building constructed at Fort Michilimackinac and named in honor of Ste. Anne. |
| 1744 |
Tensions between French and English erupt into "King George's War." |
| 1747-1748 |
Fort repaired and expanded. |
| 1747 |
American Indian unrest and attacks on French at Michilimackinac and Detroit. |
| 1751 |
Construction of new guardhouse authorized. Expansion of fort toward lake authorized. |
| 1752 |
Charles Langlade leads party of Odawa and French in a successful raid on the aggressive English traders at Pickawillany in Ohio country. |
| 1753 |
Large Indian council held at Fort Michilimackinac. Each nation agrees to ally with the French. |
| 1755 |
Warriors from Michilimackinac help defeat General Edward Braddock at Fort Duquesne in Pennsylvania. |
| 1760 |
French defeated at Montreal, following the fall of Quebec in 1759. New France passes into British hands. Troops from Fort Michilimackinac present at both battles. French evacuate fort in October. |
| 1761 |
British take control of Fort Michilimackinac in September following French and Indian War. |
| 1763 |
Fort Michilimackinac attacked and captured by American Indian tribes as part of Pontiac's Uprising.
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| 1764 |
Fort Michilimackinac returned to the British by American Indians. British arrive aboard the Schooner Gladwin, the first sailing vessel to call at the straits since the ill-fated Griffin in 1679. |
| 1765 |
Jesuit mission of St. Ignace at L'Arbre Croche closes. Development of Michilimackinac suburbs begins. |
| 1766 |
Commandant Robert Rogers dispatches exploration party in search of northwest water passage to Pacific Ocean. |
| 1770 |
Soldiers' Barracks and Commanding Officer's House completed. |
| 1772 - 1775 |
Major repairs and improvement to walls, platforms, stairs and gates. |
| 1773 |
New King's Storehouse completed. |
| 1774 |
Commandant DePeyster holds council of Ojibwa and Sioux at Michilimackinac. |
| 1779 |
Clearing of land begins on Mackinac Island in October. First house moved in November. |
| 1780 - 1781 |
Fort Michilimackinac moved to Mackinac Island. What is not moved is burned. |